Description | PolaritySensitiveIndicatorofViABIlity(pSIVA(AnnexinXII))isanAnnexinbased,polaritysensitiveprobeforthespatiotemporalorkineticanalysisofapoptosisandotherformsofcelldeath.pSIVA(AnnexinXII)bindingisreversIBLeenablingresearchers,forthefirsttime,todetecttransientPSexposurewhichisassociatedwithnormalphysiologicalprocessesaswellaswithreversibleorrescuableapoptosiscelldeathevents.pSIVA(AnnexinXII)isconjugatedtoIANBD,apolaritysensitivedyethatfluorescesonlywhenpSIVAisboundtothecellmembrane.pSIVA"smembrane-bounddependentfluorescenceandreversiblebindingpropertiesareatechnologicalleapfordetectingPSexposureandofferadditionalinformationontheapoptosispathwayandcellsurvivalcomparedtoAnnexinVconjugates.AnnexinVbindingisnonreversible. |
KitType | FlowCytometryKit |
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ApplicationNotes | PleaseseePDFmanualattachedforspecificusageinformation.UseinFlowcellsurfacereportedinscientificliterature(PMID24804954) | |
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Storage | Storageiscontentdependent. |
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