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Hello Bio/Eplerenone/HB2527/10mg

Productoverview

  • Name
    Eplerenone
  • Shortdescription
    SelectivemineralcorticoidreceptorantagoNIST
  • BIOLOGicaldescription
    Selectivemineralcorticoidreceptorantagonist(IC50=990nM).Showslittletonoeffectatandrogen,estrogenorprogesteronereceptors.Showscardioprotectiveandanti-apoptoticeffects.
  • Biologicalaction
    Antagonist
  • Purity
    >99%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylicacidγ-lactonemethylester
  • MolecularWeight
    414.5
  • Chemicalstructure
    Eplerenone
  • MolecularFormula
    C24H30O6
  • CASNumber
    107724-20-9

StoringandUsingYourProduct

  • Storageinstructions
    roomtemperature
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforEplerenone

  • Recentstudieswitheplerenone,anovelselectivealdosteronereceptorantagonist.

    McMahonEG(2001)CurrOpinPharmacol1(2):190-6.
    PubMedID:11714095

  • Anewmodeofmineralocorticoidreceptorantagonismbyapotentandselectivenonsteroidalmolecule.

    FagartJetal(2010)JBiolChem285(39):29932-40.
    PubMedID:20650892

  • Eplerenoneattenuatedcardiacsteatosis,apoptosisanddiastolicdysfunctioninexperimentaltype-IIdiabetes.

    Ramã?rezEetal(2013)CardiovascDiabetol12:172
    PubMedID:24261558
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