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Hello Bio/SL 0101-1/HB0584/1mg

Productoverview

  • Name
    SL0101-1
  • Shortdescription
    Selectivep90ribosomalS6kinaseinhibitor
  • BIOLOGicaldescription
    Selectivep90ribosomalS6kinase(RSK)inhibitor(IC50=89nMforRSK2).Showsanti-proliferativeactionsagainstcancercelllines.
  • Alternativenames
    SL0101
  • Biologicalaction
    Inhibitor
  • Purity
    >95%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    3-[(3,4-Di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydro-2-(4-hydroxyphenyl)-4H-1benzopyran-4-one
  • MolecularWeight
    516.46
  • Chemicalstructure
    SL 0101-1 [77307-50-7]
  • MolecularFormula
    C25H24O12
  • CASNumber
    77307-50-7

StoringandUsingYourProduct

  • Storageinstructions
    -20°C
  • Solubilityoverview
    solubleinethanol(20mM)orDMSO(10mM)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforSL0101-1

  • Identificationofthefirstspecificinhibitorofp90ribosomalS6kinase(RSK)revealsanunexpectedroleforRSKincancercellproliferation.

    SmithJAetal(2005)CancerRes65(3):1027-34.
    PubMedID:15705904

  • InhibitionofRSK/YB-1signalingenhancestheanti-cancereffectofenzalutamideinprostatecancer.

    ShiotaMetal(2014)Prostate74(9):959-69.
    PubMedID:24740858

  • Theselectivityofproteinkinaseinhibitors:afurtherupdate.

    BainJetal(2007)BiochemJ408(3):297-315.
    PubMedID:17850214
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