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Hello Bio/VU 0360223/HB0637/

Productoverview

  • Name
    VU0360223
  • Shortdescription
    mGlu5negativeallostericmodulator
  • BIOLOGicaldescription
    mGlu5receptornegativeallostericmodulator(IC50=61nM).ExhibitslittleornoactivityatmGlu1-4andmGlu7-8receptors.Blood-brainbarrierpermeable.
  • Biologicalaction
    NAM
  • Purity
    >99%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    3-Fluoro-5-(2-methyl-5-benzothiazolyl)-benzonitrile
  • MolecularWeight
    268.31
  • Chemicalstructure
    VU 0360223 [1274859-33-4]
  • MolecularFormula
    C15H9FN2S
  • CASNumber
    1274859-33-4

StoringandUsingYourProduct

  • Storageinstructions
    roomtemperature
  • Solubilityoverview
    solubleinDMSO(25mM)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforVU0360223

  • (3-Cyano-5-fluorophenyl)biarylnegativeallostericmodulatorsofmGlu(5):DiscoveryofanewtoolcompoundwithactivityintheOSSmousemodelofaddiction.

    LindsleyCWetal(2011)ACSChemNeurosci2(8):471-482.
    PubMedID:21927650
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