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Hello Bio/GABA/HB0882/

Productoverview

  • Name
    GABA
  • Shortdescription
    Endogenousinhibitoryneurotransmitter
  • BIOLOGicaldescription

    Mainendogenousinhibitoryneurotransmitter.ActivatesionotropicGABAAandGABAA-ρreceptorsandmetabotropicGABABreceptors.Alsoinducesα-cell-mediatedβ-likeendocrinecellneogenesisinvivo.

  • Biologicalaction
    Inhibitor
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    4-Aminobutyricacid
  • MolecularWeight
    103.12
  • Chemicalstructure
    GABA [56-12-2]
  • MolecularFormula
    C4H9NO2
  • CASNumber
    56-12-2
  • PubChemidentifier
    119
  • SMILES
    C(CC(=O)O)CN
  • InChi
    InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
  • InChiKey
    BTCSSZJGUNDROE-UHFFFAOYSA-N
  • MDLnumber
    MFCD00008226

StoringandUsingYourProduct

  • Storageinstructions
    Roomtemperature
  • Solubilityoverview
    Solubleinwater(100mM)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforGABA

  • GABAcreceptors:relativelysimpletransmitter-gatedionchannels?

    JohnstonGA(1996)TrendsPharmacolSci17(9):319-23.
    PubMedID:8885697

  • GABAandGABAreceptorsinthecentralnervoussystemandotherorgans.

    WatanabeMetal(2002)IntRevCytol213:1-47.
    PubMedID:11837891

  • GABA:adominantneurotransmitterinthehypothalamus.

    DecavelCetal(1990)JCompNeurol302(4):1019-37.
    PubMedID:2081813

  • SynthesisofneurotransmitterGABAviatheneuronaltricarboxylicacidcycleiselevatedinratswithlivercirrhosisconsistentwithahighGABAergictoneinchronichepaticencephalopathy.

    LekeRetal(2011)JNeuRochem117(5):824-32.
    PubMedID:21395584

  • Long-TermGABAAdmiNISTrationInducesAlphaCell-MediatedBeta-likeCellNeogenesis.

    Ben-Othmanetal(2017)Cell.168(1-2)::73-85
    PubMedID:27916274
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