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Tonbo Biosciences/Recombinant Human sTRAIL Receptor 1 (Carrierfree)/217159U050 /50 µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Tonbo Biosciences/Recombinant Human sTRAIL Receptor 1 (Carrierfree)/217159U050 /50 µg

TRAILReceptor1(DR4,TNFRSF10A,CD261,APO2)isatypeItransmembraneproteinbelongingtotheTNFreceptorsuperfamily.ItcontainsacytoplasmicdeathdomainandisoneofthefourreceptorsthatbindTRAILtoinitiateapoptosis.TRAILR1mediatedapoptosisinvolvesasignalingcomplexthatincludesFADDandcaspases8and10.TRAILR1expressioncanbeinducedbyNF-kappaB.
NameRecombinantHumansTRAILReceptor1(Carrier-free)
Cat.No.21-7159
AlternativeNamesTRAILR1,DR4,TNFRSF10A,CD261,APO2
AminoAcidSequenceSGTGAAAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRSERPGACNRCTEGVGYTNASQQLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSTGCPRGMVKVKDCTPWSDIECVHKESGNGHN
AuthenticityVerifiedbyN-terminalandMassSpectrometryanalyses(whenapplicable).
BioactivityTheexpectedED50is0.4-0.5ug/ml,asdeterminedbymeasuringitsabilitytoinhibitapoptosisinLN-18cells.
EndotoxinLevelEndotoxinlevelis<0.1 ng/μg of protein (<1 EU/μg).
MolecularMassRecombinantHumansTRAILReceptor1isa22.7kDaproteinconsistingof215aminoacidsthatcorrespondtothecysteine-richextracellulardomain.
ProteinContentVerifiedbyUVSpectroscopyand/orSDS-PAGEgel.
Purity(%)98
SourceE.coli
ReactivityHuman
ResearchAreasTNFSuperfamily,ImmuneSystem,Cancer,Receptors
ReconstitutionSeeCertificateofAnalysis(COA)forlotspecificreconstitutioninformation.
ApplicationsBioassay

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