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TheL243antibodyreactswithamemberofthehumanMHCClassIIantigens,HLA-DR.TheHLA-DRantigenisexpressedonBlymphocytes,activatedTlymphocytes,activatedNKcells,monocytes,macrophages,otherantigenpresentingcellsandprogenitorcells.TheL243antibodyisspecifictoanepitopeonthealphasubunitoftheheterodimericHLA-DRproteinandbindsadifferentepitopethantheLN3antibodyclone.Itdoesnotcross-reactwithHLA-DPorHLA-DQ.Thisantibodyisreportedtobecross-reactivewithnon-humanprimatesincludingChimpanzee,Cynomolgus,RhesusandBaboon.Pleasechoosetheappropriateformatforeachapplication.
| Name | APC-Cyanine7Anti-HumanHLA-DR(L243) |
|---|---|
| Cat.No. | 25-9952 |
| AlternativeNames | No |
| GeneID | 3122 |
| Clone | L243 |
| Isotype | MouseIgG2a,kappa |
| Reactivity | Human |
| CrossReactivity | Chimpanzee,Cynomolgus,Rhesus,Baboon,SquirrelMonkey,AfricanGreenMonkey |
| Format | APC-Cyanine7 |
| Applications | FlowCytometry |
| Citations* | BrodskyFM.1984.Immunogenetics.19(3):179-194. RobbinsPA,EvansEL,DingAH,WarnerNLandBrodskyFM.1987.HumanImmunol.18(4):301-313. PoulinLF,ReyalY,Uronen-HanssonH,SchramlBU,SanchoD,MurphyKM,HakanssonUK,MoitaLF,AgaceWW,BonnetDandReiseSousaC.2012.Blood.119(25):6052-6062.(Flowcytometry) ShioMT,HassanGS,ShahWA,NadiriA,ElFakhryY,LiHandMouradW.2014.JImmunol.192(6):2543-2550.(Flowcytometry) BigleyV,McGovernN,MilneP,DickinsonR,PaganS,CooksonS,HaniffaMandCollinM.2015.JLeukocBiol.97(4):627-634.(Flowcytometry) GoodierMRandLondeiM.2000.JImmunol.165(1):139-147.(Depletion) Kalka-MollWM,TzianabosAO,BryantPW,NiemeyerM,PloeghHLandKasperDL.2002.JImmunol.169(11):6149-6153.(Blocking) |