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TheL17F12antibodyisspecificforhumanCD5,a67kDtransmembraneglycoproteinthatisexpressedonmostthymocytes,matureTcells,andasubsetofBcells.CD5isamemberofthescavengerreceptorsuperfamilyandispresentonapproximately70%ofnormalperipheralbloodlymphocytes.CD5isinvolvedinmodulatingantigenreceptorsignalinginbothTandBcellsandactsthroughbindingofCD72,itsreceptorexpressedonBcells.
| Name | PerCPAnti-HumanCD5(L17F12) |
|---|---|
| Cat.No. | 67-0058 |
| AlternativeNames | Leu-1,T1 |
| GeneID | 921 |
| Clone | L17F12 |
| Isotype | MouseIgG2a,kappa |
| Reactivity | Human |
| CrossReactivity | No |
| Format | PerCP |
| Applications | FlowCytometry |
| Citations* | KnappW,DorkenB,etal.eds.1989.LeucocyteTypingIV:WhiteCellDifferentiationAntigens.OxfordUniversityPress.NewYork. GadolNandAultKA.1986.ImmunolRev.93:23-34. AntinJH,EmersonSG,MartinP,GadolNandAultKA.1986.JImmunol.136:505-510. RaabM,YamamotoMandRuddCE.1994.MolCellBiol.14(5):2862-2870. LydyardPM,LamourA,MacKenzieLE,JaminC,MaggedRAandYouinouP.1993.ImmunolLett.38(2):159-166. McKennaRW,WashingtonLT,AquinoDB,PickerLJandKroftSH.2001.Blood.98(8):2498-2507.(FlowCytometry) ButmarcJR,KoureaHP,LeviEandKadinME.1998.AmJClinPath.109(6):682-688.(Immunohistochemistry-paraffin-embeddedtissue) |