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The2H7antibodyreactswithhumanCD20,expressedbypre-Bcells,restingandactivatedBcells,folliculardendriticcellsandasmallsubsetofTcells,butnotonplasmacells.CD20isa33-37kDatransmembraneproteinwhichisdifferentiallyphosphorylatedinrestingandactiveBcells.TheCD20moleculeplaysaroleinregulatingB-cellactivation.
The2H7antibodyisreportedtobecross-reactivewithseveralnon-humanspeciesincludingBaboon,Chimpanzee,CynomolgusandRhesus.Pleasechoosetheappropriateformatforeachapplication.
| Name | APC-Cyanine7Anti-HumanCD20(2H7) |
|---|---|
| Cat.No. | 25-0209 |
| AlternativeNames | B1,Leu-16,Bp35 |
| GeneID | 931 |
| Clone | 2H7 |
| Isotype | MouseIgG2b,kappa |
| Reactivity | Human |
| CrossReactivity | Baboon,Chimpanzee,Cynomolgus,Rhesus,PigtailedMacaque,CapuchinMonkey,SquirrelMonkey |
| Format | APC-Cyanine7 |
| Applications | FlowCytometry |
| Citations* | LiuAY,RobinsonRR,MurrayJrED,LedbetterJA,HellstromIandHellstromKE.1987.JImmunol.139(10):3521-3526. SchlossmanS,BloumsellL,etal.eds.1995.LeucocyteTypingV:WhiteCellDifferentiationAntigens.OxfordUniversityPress.NewYork. DeansJP,KaltE,LedbetterJA,SchievenGL,BolenJBandJohnsonP.1995.JBiolChem.270:22632-22638.(Flowcytometry) PolyakMJandDeansJP.2002.Blood.99(9):3256-3262.(Flowcytometry,Immunoprecipitation) BrownKN,TrichelAandBarratt-BoyesSM.2007.JImmunol.178(11):6958-6967.(Flowcytometry-Rhesus) 新闻动态
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