MolecularWeight: | 127.14 |
Formula: | C6H9NO2 |
Purity: | ≥98% |
CAS#: | 1423058-85-8 |
Solubility: | DMSOupto100mM |
ChemicalName: | N-hydroxycyclopent-1-enecarboxamide |
Storage: | Powder:4oC1year.DMSO:4oC3month;-20oC1year. |
BRD9757isahighlypotentandselectiveHDAC6inhibitorwithanIC50of30nMtowardHDAC6.Ithas>20-foldselectivityforclassIand>400-foldselectivityforclassIIHDACstested.BRD9757isabsenceofasurface-bindingmotif.ItdemonstratesthathighselectivityandpotentinhibitionofHDAC6canbeachievedthroughcarefulchoiceoflinkerelementonly.BRD9757canbeusedasausefultoolforprobingthebiologicalfunctionsandrelevanceofthedifferentHDACisoforms,andservesasabasisfornewselectiveinhibitorsofotherHDACisoforms.
HowtoUse:
Invitro:BRD9757wassuggestedtobeusedat10µMfinalconcentrationinvitroandincellularassays.
Invivo:n/a
Reference:
BRD9757_spec.pdf
BRD9757_MSDS.pdf
Productsareforresearchuseonly.Notforhumanuse.
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