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Axolbio/Human iPSC-Derived Neural Stem Cells (Female)/ax0019/1 Ea

HumaniPSC-DerivedNeuralStemCells(1.5millioncells/vial)and1bottleofNeuralPlating-XFMedium(30mL)

Description:

AxolHumaniPSC-DerivedNeuralStemCells

AxolHumaniPSC-DerivedNeuralStemCells(NSCs)arederivedfromintegration-free,inducedpluripotentstemcells(iPSCs)underfullydefinedneuralinductionconditions.TheNSCsexpresstypicalMarkersofcerebralcorticalneuralstemandProgenitorcellssuchasPAX6,FOXG1andnestin,andspontaneouslyformpolarizedneuraltube-likerosettestructureswhenplatedasamonolayerinculture(seebelow).Additionally,AxolNSCsarecapableofgeneratingaspectrumofcerebralcorticalexcitatoryandinhibitoryneuronsthatareelectricallyactiveandhavetheABIlitytoformfunctionalsynapsesandcircuitsinvitro.Afterthawingandplating,theneuralstemcellsterminallydifferentiatetoacquirematureelectrophysiologicalproperties,andformfunctionalsynapticnetworksoveraperiodof40~50days.

AxolNSCsareeasytodifferentiatetoneuronsormixedneuralcelltypes,followingourprotocolsandusingourtailoredmediaandreagentbundles.AhighlypurepopulationofneuronscanbegeneratedfromAxolNSCsfollowingthesynchronousdifferentiationprotocol.Usingourspecializedcoatingreagents,neuronsderivedfromAxolNSCscanbemaintainedinculturelong-term(>1year).NSCsareavailablefrommultipledonorstosuityourresearchneedsandhavebeencharacterizedextensively.

ClickheretoseethedataonAxolNeuralStemCells

ProductSpecification:

StartingmaterialDermalfibroblast
DonorgenderFemale
Donorageatsampling64yrs
KaryotypeNormal
ReprogrammingmethodEpisomalvector
InductionmethodMonolayer&chemicallydefinedmedium
GeneticmodificationNone
Size≥1.5millioncells
Kitcomponents1vialofNeuralStemCells(≥1.5millioncells)and1bottleofNeuralPlating-XFMedium(30mL)
GrowthpropertiesAdherent
ShippingconditionsDryice
StorageconditionsLiquidnitrogen
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