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Axolbio/axolGEM iPSC-Derived Neural Stem Cells MAPT R406W HOM/ax0320/1 Ea188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Axolbio/axolGEM iPSC-Derived Neural Stem Cells MAPT R406W HOM/ax0320/1 Ea

axolGEMiPSC-DerivedNeuralStemCellsMAPTR406WHOM(1.5millioncells)andNeuralPlating-XFMedium(30mL)

Description:

HumaniPSC-DerivedNeuralStemCellsthathavebeengeneticallyeditedusingCRISPR-Cas9technologytointroducetheR406Wmutation(CGG>TGG)intotheMAPTgene.ThislineishomozygousfortheR406Wmutationsobothallelescontainthemutation.Clickontheproductimagestoseethedataandfurtherdetails. 

TheR406WmutationinMAPThasbeenimplicatedinfamilialfrontotemporaldementiaandparkinsonism (Hutton etal.,1998;Behnametal.,2015)andhasbeenseeninpatientswithclinicalpresentationresemblingAlzheimer"sdisease(Rademakersetal.,2003; Lindquistetal.,2008).TheR406WmutationreducestheABIlityofMAPT/tautobindtomicrotubulesinvitro(Hongetal.,1998). 
ClickheretoseemoredataonAxolNeuralStemCells

ProductSpecification:

StartingmaterialDermalfibroblast
DonorgenderFemale
Donorageatsampling64yrs
KaryotypeNormal
ReprogrammingmethodEpisomalvector
InductionmethodMonolayer&chemicallydefinedmedium
GeneticmodificationHomozygousfortheMAPTR406Wmutation(CGG>TGG)
GeneticmodificationContainsapuromycinresistancecassette(intronic)
Size≥1.5millioncells
Kitcomponents1vialofaxolGEMNeuralStemCells(≥1.5millioncells)and1bottleofPlating-XFMedium(30mL)
GrowthpropertiesAdherent
ShippingconditionsDryice
StorageconditionsLiquidnitrogen
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