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Adipogen/Transthyretin GST (human) (rec.)/YIF-LF-P0054/0.5 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Adipogen/Transthyretin GST (human) (rec.)/YIF-LF-P0054/0.5 mg

More Information
Product Details
Synonyms TTR; ATTR; PALB; TBPA; Prealbumin; Transthyretin
Product Type Protein
Properties
Source/Host E. coli
Crossreactivity Human
Purity ≥90% (SDS-PAGE)
Formulation Lyophilized from 20mM HEPES, pH7.0.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability After reconstitution, store at -80°C.
Documents
MSDS No
Product Specification Sheet
Datasheet Download PDF
Transthyretin (TTR) , generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
Product References
1) Hamilton, J.A. and Benson, M.D. (2001) Cell. Mol. Life Sci. 58, 1491-1521. (General)
2) Shirahama, T. et al. (1982) Am. J. Path. 107, 41-50. (General)
3) Episkopou, V. et al. (1993) Proc. Nat. Acad. Sci. 90, 2375-2379. (General)
4) Saraiva, M.J.M. (1995) Hum. Mutat. 5, 191-196. (General)
5) Pfeffer, B. et al. (2004) Mol. Vis. 10, 23-30. (General)
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