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Rockland/AP3S1 Antibody/600401Y25/100 µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Rockland/AP3S1 Antibody/600401Y25/100 µg

AP3S1AntibodyProperties

Description
Anti-AP3S1(RABBIT)Antibody-600-401-Y25
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
Human,mouse,rat
Clonality
Polyclonal
Application
ELISA:1:10,000-1:20,000
IFMicroscopy:20µg/mL
WesternBlot:1-2µg/mL
Immunohistochemistry:2.5µg/mL
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
1mg/mLbyUVabsorbanceat280nm
Buffer
0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2
Preservative
0.02%(w/v)SodiumAzide
Stabilizer
None
GeneName
AP3S1
RelevantLinks
UniProtKB-Q92572
GeneID-1176
NCBI-NP_001275

AP3S1AntibodyDescription

Background
AP3S1belongstotheadaptorcomplexes3(AP3)smallsubunitfamilywhichisnotclathrin-associated.ThecomplexisassociatedwiththeGolgiregionaswellasmoreperipheralstructures.ItfacilitatesthebuddingofvesiclesfromtheGolgimembraneandmaybedirectlyinvolvedintraffickingtolysosomes.AP3isanheterotetramercomposedoftwolargeadaptins(AP3D1,AP3B1orAP3B2),amediumadaptin(AP3M1orAP3M2)andasmalladaptin(APS1orAP3S2).AP3S1InteractswithAGAP1andmayplayanimportantroleincarcinoma.
Synonyms
AP3S1Antibody,CLAPS3,Sigma3A,CLAPS3,AP-3complexsubunitsigma-1,AP-3complexsubunitsigma-3A,Sigma3A-adaptin
Immunogen
Anti-AP3S1antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha19aminoacidsyntheticpeptideneartheinternalregionofhumanAP3S1.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AP3S1AntibodyhasbeentestedforuseinELISA,WesternBlotting,ImmunohistochemistryandImmunofluorescence.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately22kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-AP3S1Antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.AtleastthreeisoformsofAP3S1areknowntoexist;thisantibodywilldetectthetwolargerisoforms.AP3S1antibodyispredictedtonotcross-reactwithotherAP3proteinfamilymembers.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.Theprospectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

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