Rockland/ARTS Antibody/600401Y64/100 µg

ARTSAntibodyProperties

Description

Anti-ARTS(RABBIT)Antibody-600-401-Y64

Host

Rabbit

TargetSpecies

Human

KnownCrossReactivity

Human

Clonality

Polyclonal

Application

ELISA:1:20,000
IFMicroscopy:20µg/mL
WesternBlot:2µg/mL
Immunohistochemistry:2µg/mL

PhysicalState

Liquid(sterilefiltered)

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Concentration

1mg/mLbyUVabsorbanceat280nm

Buffer

0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2

Preservative

0.02%(w/v)SodiumAzide

Stabilizer

None

GeneName

SEPT4

RelevantLinks

UniProtKB-O43236
GeneID-5414
NCBI-AAG45673

ARTSAntibodyDescription

Background

Apoptosisisrelatedtomanydiseasesanddevelopment.Mitochondrialproteins,suchascytochromec,Apaf-1,andAIFplayimportantroleinapoptosis.Anovelmitochondrialseptin-likeproteinwasidentifiedrecentlyanddesignatedARTSforapoptosisrelatedproteininTGF-betasignalingpathway.ARTSthatisencodedbythehumanseptinH5/PNUTL2/CDCrel2bgeneislocatedtomitochondriaandtranslocatestothenucleuswhenapoptosisoccurs.ARTSisexpressedinmanytissues.ItenhancescelldeathinducedbyTGF-betaand,toalesserextent,byotherapoptoticagents,suchasTNF-aandFasligand.

Synonyms

ARTSAntibody,H5,ARTS,MART,SEP4,CE5B3,PNUTL2,hucep-7,BRADEION,hCDCREL-2,Septin-4,Apoptosis-relatedproteinintheTGF-betasignalingpathway

Immunogen

Anti-ARTSantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithasyntheticpeptidecorrespondingtoaminoacidsneartheN-terminusofhumanARTS.

ImmunogenType

Peptide

StorageCondition

Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-ARTSAntibodyhasbeentestedforuseinELISA,WesternBlotting,ImmunohistochemistryandImmunofluorescence.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately55kDainWesternBlotsofspecificcelllysatesandtissues.

Purity/Specifity

Anti-ARTSAntibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.CrossreactivitywithARTSfromothersourceshasnotbeendetermined.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.Theprospectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

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Rockland/ARTS Antibody/600401Y64/100 µg

ARTSAntibodyProperties

ARTSAntibodyDescription