Rockland/Aldh3A2 Antibody/600401Y03/100 µg

Aldh3A2AntibodyProperties

Description

Anti-Aldh3A2(RABBIT)Antibody-600-401-Y03

Host

Rabbit

TargetSpecies

Human

KnownCrossReactivity

Human,mouse

Clonality

Polyclonal

Application

ELISA:1:10,000-1:20,000
WesternBlot:1-2µg/mL

PhysicalState

Liquid(sterilefiltered)

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Concentration

1mg/mLbyUVabsorbanceat280nm

Buffer

0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2

Preservative

0.02%(w/v)SodiumAzide

Stabilizer

None

GeneName

ALDH3A2

RelevantLinks

UniProtKB-P51648
GeneID-224
NCBI-NP_001026976

Aldh3A2AntibodyDescription

Background

Aldh3A2isamemberofthealdehydedehydrogenasesuperfamily,agroupofNAD(P)(+)-dependentenzymesthatcatalyzetheoxidationofawidespectrumofaliphaticandaromaticaldehydes.Aldehydedehydrogenaseenzymesarethoughttoplayamajorroleinthedetoxificationofaldehydesgeneratedbyalcoholmetabolismandlipidperoxidation.Aldh3A2catalyzestheoxidationoflong-chainaliphaticaldehydestofattyacids.MutationsintheAldh3A2genecauseSjogren-Larrsonsyndrome,aninheritedneurocutaneousdisorder.Patientswiththisdisorderdisplayichthyosis,mentalretardationandspasticdiplegia.Thepathogenesisofthecutaneousandneurologicalsymptomsisthoughttoresultfromabnormallipidaccumulationinthemembranesofskinandbrain,theformationofaldehydeSchiffbaseadductswithamine-containinglipidsorproteins,ordefectiveeicosanoidmetabolism.

Synonyms

Aldh3A2Antibody,SLS,FALDH,ALDH10,Fattyaldehydedehydrogenase,Aldehydedehydrogenase10

Immunogen

Anti-Aldh3A2antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha14aminoacidsyntheticpeptideneartheC-terminusofthehumanAldh3A2.

ImmunogenType

Peptide

StorageCondition

Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-Aldh3A2AntibodyhasbeentestedforuseinELISAandWesternBlotting.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately55kDainWesternBlotsofspecificcelllysatesandtissues.

Purity/Specifity

Anti-Aldh3A2Antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.AtleastfourisoformsofAldh3A2areknowntoexist.Thisantibodyispredictedtohavenocross-reactivitytoAldh3A1.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.Theprospectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

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Rockland/Aldh3A2 Antibody/600401Y03/100 µg

Aldh3A2AntibodyProperties

Aldh3A2AntibodyDescription