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Kerafast/Anti-ADAM12 (mouse), Cytoplasmic Domain Antibody/EHS003/100uL188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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产品资料

Kerafast/Anti-ADAM12 (mouse), Cytoplasmic Domain Antibody/EHS003/100uL

ThisrabbitIgGpolyclonalantibodywasgeneratedagainsttheGST-ADAM12-cytoplasmictailandisspecificforthecytoplasmicdomainofmouseADAM12.

TheADAM(ADisintegrinAndMetalloproteaseDomain)familyisauniquegroupofproteinsthathastheABIlitytocleaveorshedextracellularportionsoftransmembraneproteins.Inaddition,ADAMsareinvolvedincell-cellandcell-matrixinteractions(e.g.,fertilization,muscledevelopmentandneurogenesis).

LiketheotherADAMmembers,ADAM12isstructurallyrelatedtosnakevenomdisintegrins.Ithastwoalternativelysplicedtranscripts:ashortersecretedformandalongermembrane-boundform.ADAM12hasbeenimplicatedinbreastandprostatecancer.

FromthelaboratoryofCarlP.Blobel,MD,PhD,HospitalforSpecialSurgery.

The InvestigatorPartofTheInvestigator"sAnnexeprogram.

Specifications
ProductType: Antibody
Antigen: GST-ADAM12cytoplasmicdomain
AccessionID: D50411
Isotype: IgG
Clonality: Polyclonal
Reactivity: Mouse
Immunogen: GST-cytocorrespondingtothecytoplasmicdomainofmouseADAM12
SpeciesImmunized: Rabbit
Epitope: Cytoplasmicdomain
PurificationMethod: Serum,notpurified
TestedApplications: WB(1:500)
Storage: -80C
Shipped: Dryice
Research
AntibodySpeciesReactivitySpecificity
ADAM9HumanCytoplasmicDomain
ADAM9MouseCytoplasmicDomain
ADAM12MouseCytoplasmicDomain
ADAM15HumanCytoplasmicDomain
ADAM15MouseCytoplasmicDomain
ADAM15HumanExtracellularDomain
ADAM15MouseDisintegrinDomain
ADAM17MouseCytoplasmicDomain
ADAM17MouseProdomain
ADAM19MouseCytoplasmicDomain
ADAM28MouseCytoplasmicDomain
ADAM28MouseExtracellularDomain
SNX9MouseCytoplasmicDomain
Provider
FromthelaboratoryofCarlP.Blobel,MD,PhD,HospitalforSpecialSurgery.
References
  1. Inoue,D.;Reid,M.;Lum,L.;Krätzschmar,J.;Weskamp,G.;Myung,Y.M.;Baron,R.;Blobel,C.P.Cloningandinitialcharacterizationofmousemeltrinbetaandanalysisoftheexpressionoffourmetalloprotease-disintegrinsinbonecells.J.Biol.Chem.1998,273,4180-4187.

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