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Enzolifesciences/<em>E. coli</em> host cell proteins polyclonal antibody/ENZ-ABS262-0100/100µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Enzolifesciences/E. coli host cell proteins polyclonal antibody/ENZ-ABS262-0100/100µg

ProductSpecification:

AlternativeName:HCP
 
Host:Rabbit
 
Immunogen:E.colihostcellproteins.
 
Speciesreactivity:E.coli
 
Specificity:RecognizesE.colihostcellproteins.
 
Applications:WB
 
PurityDetail:ProteinAaffinitypurified.
 
Formulation:Liquid.InPBScontaining10ppmKathon.
 
Use/StABIlity:Stableforonemonthat4°C,stableforatleast12monthsat-20°C.
 
Handling:Avoidfreeze/thawcycles.
 
Shipping:ShippedonBlueIce
 
ShortTermStorage:+4°C
 
LongTermStorage:-20°C
 
ScientificBackground:Hostcellproteins(HCPs)areproteinsuniquetothehostcellusedinBIOLOGicsproductionandareconsideredtobeapotentiallyhazardouscontaminantwhenincludedinthefinalrecombinantproduct.Thereisarangefrom4,300genesinE.colito30,000genesinCHOorNS0celllinesthatmaybeexpressedalongwiththedesiredrecombinantproduct,andatleastasmallsub-populationoftheseproteinswillnormallyco-purifywiththeproteinofinterest.CharacterizationoftheseHCPsisimportantbecausetherearepotentialsafetyriskswhentheyareincludedinatherapeuticproduct,andtheforeignnatureoftheproteinscanelicitanimmuneresponseinhumans.AntibodiesraisedagainsthostcellproteinscanbeusedtodetectHCPsusingWesternblotanalysis.
 
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