| AlternativeName: | ZU5anddeathdomain-containinginhibitorofNF-κB,Unc-5homologC(C.elegans)-like,UNC5CL |
| Host: | Rabbit |
| Immunogen: | RecombinanthumanZUDdomain(aa402-518). |
| UniProtID: | Q8IV45 |
| Speciesreactivity: | Human,Mouse |
| Applications: | ICC,IP,WB |
| RecommendedDilutions/Conditions: | Immunocytochemistry(1:100) Immunoprecipitation(1:200) WesternBlot(1:1,000) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| PurityDetail: | ProteinA-affinitypurified. |
| Formulation: | Liquid.InPBScontaining0.02%sodiumazide. |
| Use/StABIlity: | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Handling: | Avoidfreeze/thawcycles.Afterreconstitution,preparealiquotsandstoreat-20°C. |
| Shipping: | ShippedonBlueIce |
| ShortTermStorage: | +4°C |
| LongTermStorage: | -20°C |
| ScientificBackground: | ZUDiscytoplasmicproteinwithaZU5anddeathdomain.ItinteractswiththeNF-κBsubunitp105andtransactivatorp65andinhibitsNF-κB-dependenttranscriptionwhenitsoverexpressed.ZUDseemstobeainhibitorofNF-κBsignalling,andenhancecelldeathtoapoptoticstimulilikeTNFandTRAIL. |
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