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Tocris/Leupeptin hemisulfate/1167/25/25 mg

Description:Inhibitstrypsin-like/cysteineproteases
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ReversIBLeinhibitoroftrypsin-likeandcysteineproteasessuchascalpain.Showntoinhibitactivation-inducedprogrammedcelldeath.

TechnicalData

M.Wt475.04
FormulaC20H38N6O4.½H2SO4
SequenceLLR

(Modifications:Leu-1=N-terminalAc,Arg-3=Arginal)

StorageDesiccateat-20°C
CASNumber103476-89-7
PubChemID2733491
InChIKeyCIPMKIHUGVGQTG-VFFZMTJFSA-N
SmilesOS(O)(=O)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto10mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight475.04.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.11mL10.53mL21.05mL
5mM0.42mL2.11mL4.21mL
10mM0.21mL1.05mL2.11mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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