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| Description | Delta-1actsasaligandforNotchreceptors.ItblocksthedifferentiationofprogenitorcellsintotheB-celllineagewhilepromotingcellswiththecharacteristicsofaT-cel/NK-cellprecursor. Itisexpressedinheartandpancreas,withlowerexpressioninbrainandmuscleandverylittleexpressioninplacenta,lung,liverandkidney.Delta-1isatransmembraneproteinwhichisubiquinatedbyMIB,leadingtoitsendocytosisandsubsequentdegradation.ItcontainsoneDSLdomainandeightEGF-likedomains. |
| BatchNo. | Seeproductlabel |
| Unitsize | 100µg |
| Antigen | PartialrecombinantproteinofhumanDelta-1(aminoacids18to109)withaGSTtag. |
| Clone | 4F8 |
| OtherNames | Delta-likeprotein1;DrosophilaDeltahomolog1;H-Delta-1;DLL1 |
| Accession | DLL1_HUMAN |
| Producedin | Mouse |
| Purity | ProteinGpurifiedimmunoglobulin |
| Applications | ThisantibodyisrecommendedforWBandsandwichELISA.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBandELISAagainsttheantigen. |
| Cross-reactivity | Otherspecieshavenotbeentested. |
| Blastit | Ifyouwouldliketoseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequence(makesurethatyouareselectingthesequencethatyouareinterestedin,asthesequencemaybetheprecursorratherthanthematureproteinforexample)andcopyandpasteitHEREandblast/formatit. |
| Form | LyophilisedfromPBSpH7.4 |
| Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
| Storage | Afterreconstitutionkeepaliquotsat-20°Cforhigherstabilityorat4°Cwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles. |
| ExpiryDate | 12monthsafterpurchase |