| Description | Semaphorin-3Aisasecretedproteinthatinducesthecollapseandparalysisofneuronalgrowthcones.Itcouldserveasaligandthatguidesspecificgrowthconesbyamotility-inhibitingmechanism.ItBindstothecomplexneuropilin-1/plexin-1.Increasedexpressionofthisproteinisassociatedwithschizophreniaandisseeninavarietyofhumantumorcelllines.Also,aberrantreleaseofthisproteinisassociatedwiththeprogressionofAlzheimer"sdisease. |
| BatchNo. | Seeproductlabel |
| Unitsize | 50µg |
| Antigen | PartialrecombinanthumanSemaphorin3A(672-770)withaGSTtag. |
| Isotype | IgG2aKappa |
| Clone | 5G9 |
| OtherNames | SemaphorinIII;SemaIII;SEMA3A;SEMAD |
| Accession | SEM3A_HUMAN |
| Producedin | Mouse |
| Purity | ProteinGpurifiedimmunoglobulin |
| Applications | ThisantibodyisrecommendedforWB,andELISA.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | SpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen. |
| Cross-reactivity | Human.Otherspecieshavenotbeentested. |
| Blastit | Toseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit. |
| Form | LyophilisedfromPBSpH7.4 |
| Reconstitution | Reconstitutein50µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
| Storage | Storelyophilizedantibodyat2-8ºC.Afterreconstitutionkeepaliquotsat-20ºCforhigherstABIlityorat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles. |
| ExpiryDate | 12monthsafterpurchase |
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