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| Description | Paired box protein Pax-5 is a member of the paired box (PAX) family of transcription factors. This family has a highly conserved DNA-binding motif known as the paired box. Paired box protein Pax-5 may play an important role in B-cell differentiation as well as neural development and spermatogenesis. It is involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. It localises to the nucleus and is expressed at early B-cell differentiation in the developing CNA and in adult testis. A defect in Paired box protein Pax-5 is a cause of acute lymphoblastic leukemia. |
| Batch No. | See product label |
| Unit size | 100 µg |
| Antigen | Partial recombinant human Paired box protein Pax-5 (192-302) with a GST tag. |
| Clone | 8F9 |
| Other Names | B-cell-specific transcription factor; BSAP; PAX5 |
| Accession | PA1B3_HUMAN |
| Produced in | Mouse |
| Purity | Protein G purified immunoglobulin |
| Applications | This antibody is recommended for WB, IHC and sandwich ELISA. The recommended dilution for this antibody is 1 µg/ml for IHC. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Specificity | Specificity has been confirmed by WB and direct ELISA against the antigen. |
| Cross-reactivity | Human. Other species have not been tested. |
| Blast it | To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it. |
| Form | Lyophilised from PBS pH 7.2 |
| Reconstitution | Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage | After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date | 12 months after purchase |