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Exalpha/Mouse anti Cytokeratin 10+13 / Keratin K10+K13/MUB0321S/1 ml188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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产品资料

Exalpha/Mouse anti Cytokeratin 10+13 / Keratin K10+K13/MUB0321S/1 ml

ProductCode

ProductName

MouseantiCytokeratin10+13/KeratinK10+K13

Size

1ml

Price(USD)

$208

Background

Cytokeratinsareasubfamilyofintermediatefilamentproteinsandarecharacterizedbyaremarkablebiochemicaldiversity,representedinHumanepithelialtissuesbyatleast20differentpolypeptides.Theyrangeinmolecularweightbetween40kDaand68kDaandisoelectricpHbetween4.97.8.TheindividualHumanCytokeratinsarenumbered1to20.ThevariousepitheliaintheHumanbodyusuallyexpressCytokeratinswhicharenotonlycharacteristicofthetypeofepithelium,butalsorelatedtothedegreeofmatuRationordifferentiationwithinanepithelium.Cytokeratinsubtypeexpressionpatternsareusedtoanincreasingextentinthedistinctionofdifferenttypesofepithelialmalignancies.TheCytokeratinantibodiesarenotonlyofassistanceinthedifferentialdiagnosisoftumorsusingimmunohistochemistryontissuesections,butarealsoausefultoolincytopathologyandflowcytometricassays.

Host

Mouse

Isotype

IgG2a

SpeciesReactivity

Feline,Human,Zebrafish,Canine

ProductUsage

DE-K13reactswithCytokeratin10and13infixedcellsandonfrozentissues,butexclusivelywithCytokeratin13informalin-fixed,paraffin-embeddedtissues.Cytokeratin10ispresentinKeratinizingstRatifiedepitheliaandindifferentiatedareasofhighlydifferentiatedsquamouscellcarcinomas,whileCytokeratin13ispresentinnon-cornifiedsquamousepithelia,exceptcornea,andtransitionalepithelialregions,withtheexceptionofbasalcelllayersofsomestRatifiedepithelia,aswellascarcinomasderivedfromthesetissues.

ProductType

PrimaryAntibodies

Applications

FlowCytometry,Immunocytochemistry,Immunohistochemistry(frozen),Immunohistochemistry(paraffin),Westernblotting

FieldsofInterest

Cytoskeleton

ProductSource

DE-K13isaMousemonoclonalIgG2a,_antibodyderivedbyfusionofSP2/0Mousemyelomacellswithspleencellsfroma(BALB/cxB6)F1MouseimmunizedwithacytoskeletalpreparationextractedfromHumanectocervicalepithelium.

ProductFormulation

Eachvialcontains1mlofculturesupernatantofmonoclonalantibodycontaining0.09%sodiumazide.

StorageConditions

Storeat4
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