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Exalpha/Mouse anti Cytokeratin 6/MUB0345S/1 ml188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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产品资料

Exalpha/Mouse anti Cytokeratin 6/MUB0345S/1 ml

ProductCode

ProductName

MouseantiCytokeratin6

Size

1ml

Price(USD)

$208

Background

Cytokeratinsareasubfamilyofintermediatefilamentproteinsandarecharacterizedbyaremarkablebiochemicaldiversity,representedinepithelialtissuesbyatleast20differentpolypeptides.Theyrangeinmolecularweightbetween40kDaand68kDaandisoelectricpHbetween4.97.8.TheindividualCytokeratinpolypeptidesarenumbered1to20.ThevariousepitheliaintheHumanbodyusuallyexpressCytokeratinswhicharenotonlycharacteristicofthetypeofepithelium,butalsorelatedtothedegreeofmatuRationordifferentiationwithinanepithelium.Cytokeratinsubtypeexpressionpatternsareusedtoanincreasingextentinthedistinctionofdifferenttypesofepithelialmalignancies.TheCytokeratinantibodiesarenotonlyofassistanceinthedifferentialdiagnosisoftumorsusingimmunohistochemistryontissuesections,butarealsoausefultoolincytopathologyandflowcytometricassays.

Host

Mouse

Isotype

IgG1

SpeciesReactivity

Human,Mouse

ProductUsage

Ks6.KA12representsanexcellentMarkerfornon-KeratinizedsquamousepitheliaandprolifeRatingcellsofepidermis(e.g.withinpsoriaticlesions).ItisalsosuitablefordiscriminationofKeratinizingandnon-Keratinizingsquamouscellcarcinomaversuse.g.poorlydifferentiatedadenocarcinoma.Ks6.KA12reactswithA-431,Detroit562andSCC-12cells.

ProductType

PrimaryAntibodies

Applications

Immunohistochemistry(frozen),Immunohistochemistry(paraffin),Westernblotting

FieldsofInterest

Cytoskeleton

ProductSource

Ks6.KA12isaMousemonoclonalIgG1antibodyderivedbyfusionofmurinemyelomacellswithspleencellsfromaMouseimmunizedwithCytokeratin6ofaHumancalluscytoskeletalpreparation.

ProductFormulation

Eachvialcontains1mlofculturesupernatantofmonoclonalantibodycontaining0.09%sodiumazide.

StorageConditions

Storeat4oC,orinsmallaliquotsat20oC.
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