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Exalpha/Mouse anti TIAM/MUB1806S/1 ml

Product Code

Product Name

Mouse anti TIAM

Size

1 ml

Price (USD)

$208

Background

Tiam1, also known as T-cell lymphoma invasion and metastasis-inducing protein 1, is a protein that in Humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, two PH domains and one Ras-binding RBD domain. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA. TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.

Host

Mouse

Isotype

IgG2b

Species Reactivity

Human

Product Usage

F5S F6.2 is a Mouse monoclonal directed anti the N-terminal region of Tiam1.

Product Type

Primary Antibodies

Applications

Immunohistochemistry (frozen),Western blotting

Fields of Interest

Cancer,Immunology,Neurobiology

Product Source

F5S F6.2 is a Mouse monoclonal IgG2b antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with T-cell lymphoma invasion and metastasis-inducing protein 1 (Tiam1).

Product Formulation

Each vial contains 1ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.

Storage Conditions

Store at 4
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