Oxytocinplaysanimportantroleintheneuroanatomyofintimacy,specificallyinsexualreproductionofbothsexes,inparticularduringandafterchildbirth.Itisreleasedinlargeamountsafterdistensionofthecervixanduterusduringlabor,facilitatingbirth,maternalbonding,and,afterstimulationofthenipples,lactation.Studieshavebeguntoinvestigateoxytocin’sroleinvariousbehaviors,includingorgasm,socialrecognition,pairbonding,anxiety,andmaternalbehaviors.Itissometimesreferredtoasthe“bondinghormone”.Thereissomeevidencethatoxytocinpromotesethnocentricbehavior,incorporatingthetrustandempathyofin-groupswiththeirsUSPicionandrejectionofoutsiders.FurThermore,geneticdifferencesintheoxytocinreceptorgenehavebeenassociatedwithmaladaptivesocialtraitssuchasaggressivebehavior.
Innon-mammalianspeciesthesebehaviorsarecontrolledbyoxytocin-likepeptides,whichdifferatpositions4and/or8. Theseoxytocin-likepeptidesincludemesotocin(withanisoleucine-8)andisotocin(glutamine-4changedtoserineandarginine-8changedtoisoleucine).Oxytocinoccursinplacentalmammals;mesotocinoccursinamphibians,reptiles,andbirds,andisotocinoccursinfishes.
OurMesotocinsolutionisaperfectcomplementforourOxytocinEIAandCLIAkitsforthoseresearchersstudying birds,reptiles,amphibians,lungfishes,coelacanthsandsomemarsupials. TherelativebindingofMesotocininourOxytocinassaysisshownbelow.
SouthernBiotech/Goat Anti-Human Lambda-Alexa Fluor® 555/2070-32/1.0 mg
vectorlabs/Biotinylated Aleuria Aurantia Lectin (AAL)/B-1395/1 mg
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Mouse IgG)/PK-6102/1 kit
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