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ubpbio/6xHis-Ube2D1 (UbcH5A)/C1400/25 µg

Ube2D1isanE2enzyme,whichispartoftheE1,E2,andE3cascaderesponsIBLeforubiquitinationofproteinsubstrates.TwootherhomologuesofUbe2D1existcalledUbe2D2andUbe2D3.Ube2D2is89%identicaltotheaminoacidsequenceofUbe2D1adUbe2D3is88%identical.Ube2D1hasbeenlinkedtocadminumtoxicity.ItmightalsoplayaroleinLDLcholesterolreceptorubiquitinationinanIdol-dependentfashion.

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Ube2D1isanE2enzyme,whichispartoftheE1,E2,andE3cascaderesponsibleforubiquitinationofproteinsubstrates.TwootherhomologuesofUbe2D1existcalledUbe2D2andUbe2D3.Ube2D2is89%identicaltotheaminoacidsequenceofUbe2D1adUbe2D3is88%identical.Ube2D1hasbeenlinkedtocadminumtoxicity.ItmightalsoplayaroleinLDLcholesterolreceptorubiquitinationinanIdol-dependentfashion.
Images:(Clickimagetoenlarge)
ProductName:6xHis-Ube2D1(UbcH5A)
AlsoKnownAs:USFT;UBCH5;UBC4/5;UBCH5A;E2(17)KB1
CatalogNo.:C1400
Size:25µg
MolecularWeight:16.6kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~95%bySDS-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheetMSDS
NCBIRefSeq:NM_003338
Image(s):(Clickimagetoenlarge)
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkers
Lane2:5µgpurified6xHis-Ube2D1(UbcH5A)
ShippingMethod:Dryiceshipping
References:1.ScheffnerM,etal.(1994)ProcNatlAcadSciUSA91,8797–8801.
2.HuibregtseJM,etal.(1995)ProcNatlAcadSciUSA92(7),2563–2567.3.GehrkeSG,etal.(2003)Blood101,3288–3293.
4.TokumotoM,etal.(2011)JToxicolSci36(2),191–200.
Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurified6xHis-Ube2D1(UbcH5A)
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