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axonmedchem/A-92/5 mg/Axon 2720

A-92

Based on 1 reference(s) in Google Scholar8101

Axon 2720

CAS [1448693-69-3]

MF C19H18N10OMW 402.41

  • Purity:99%
  • Soluble in DMSO

A-92

Description

A-92 inhibits the stress response of general control nonderepressible 2 kinase (GCN2 or EIF2AK4) (IC50 value of <0.3 μM). Possible chemotherapeutic drug for the treatment of cancer.

KEYWORDS: A-92 | supplier | GCN2 inhibitor | A92 | A 92 | CAS [1448693-69-3] | Unfolded Protein Response (EIF2 Selective) | GCN | Inhibitor | Enzymes | GCN2 | eIF2α | EIF2AK4 | General Control Nonderepressible 2 Kinase | tRNA

J Brazeau et al. Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2. ACS Med Chem Lett. 2014 Apr 10; 5(4): 282–283.
  • Certificate of Analysis
  • Material Safety Data Sheet
Cell Signaling & OncologyEC 2.7.11.1GCN
Inhibitor of GCN2 (EIF2AK4)

Chemical name

3-(1H-Indazol-6-yl)-N-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine

Parent CAS No.

[1448693-69-3]

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