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axonmedchem/A 770041/5 mg/Axon 1698

A 770041

Based on 18 reference(s) in Google Scholar91018

Axon 1698

CAS [869748-10-7]

MF C34H39N9O3MW 621.73

  • Purity:99%
  • Soluble in DMSO

A 770041

Description

Selective and orally active Src-family Lck inhibitor; A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.

Keywords: A 770041 | supplier | Lck inhibitor | A770041 | A-770041 | CAS [869748-10-7] | Non Selective (Phosphorylation Substrates) | Lck | Inhibitor | Enzymes

  • References
  • Certificates
  • Categories
  • Extra info
RF tachlewitz et al. A-770041, a novel and selective small-molecule inhibitor of Lck, prevents heart allograft rejection. J Pharmacol Exp Ther. 2005 Oct;315(1):36-41.

List of publications using A 770041 (Axon 1698) purchased from Axon Medchem

  • Certificate of Analysis
  • Material Safety Data Sheet
Cell Signaling & OncologySRCLckEC 2.7.10.2
Orally active src-family selective lck inhibitor

Chemical name

N-(4-(1-(4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

Parent CAS No.

[869748-10-7]

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