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axonmedchem/A 357300 hydrochloride/5 mg/Axon 1666

A 357300 hydrochloride

Based on 14 reference(s) in Google Scholar81014

Axon 1666

CAS [369358-07-6]

MF C15H22ClN3O3S.HClMW 396.33

  • Purity:100%
  • Optical purity:Optically pure
  • Soluble in DMSO

A 357300 hydrochloride

Description

Potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2)
J Wang et al. Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2. Cancer Res. 2003, 63(22), 7861-7869.
MJ Morowitz et al. Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models. Clin. Cancer Res. 2005, 11(7), 2680-2685.
  • Certificate of Analysis
  • Material Safety Data Sheet
AngiogenesisCardiovascularCell Signaling & OncologyMetAP2EC 3.4.11.18
MetAP2 inhibitor

Chemical name

N"-((2S,3R)-3-amino-2-hydroxy-5-(isopropylthio)pentanoyl)-3-chlorobenzohydrazide hydrochloride

Parent CAS No.

[369358-07-6]

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