Description | |
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CatalogueNumber | AB15467 |
BrandFamily | Chemicon® |
TradeName |
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Description | Anti-ARG3.1Antibody |
AlternateNames |
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BackgroundInformation | Arc/Arg3.1isanimmediate-earlygenewhosemRNAisrapidlytranscribedandtargetedtodendritesofneuronsastheyengageininformationprocessingandstorage.Arc/Arg3.1isknowntoberequiredfordurableformsofsynapticplasticityandlearning.Arc/Arg3.1hasbeenshowntobeexpressedinneuronalcellbodiesanddendritesinthebrainregionsincludingstriatumandcortexhippocampus. |
ProductInformation | |
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Format | Serum |
Presentation | Lyophilized.Reconstitutewith50μLofsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.Containsnopreservative. |
StorageandShippingInformation | |
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StorageConditions | Maintainlyophilizedmaterialfrozenat-20°Cto-70°Cforupto12monthsafterdateofreceipt.Afterreconstitutionmaintainat-20°Cinundilutedaliquotsforupto6months.Avoidrepeatedfreeze/thawcycles.Glycerol(1:1,ACSorbettergrade)canbeaddedforadditionalstABIlity. |
BIOLOGicalInformation | |
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Immunogen | SyntheticpeptidecorrespondingtoaregionwithintheC-terminusofhumanARG3.1protein. |
Host | Rabbit |
Specificity | ARG3.1[GrowthfactorARC,Activityregulatedcytoskeleton] |
SpeciesReactivity |
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AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
GeneSymbol |
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PurificationMethod | Serum |
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:Q7LC44#Requiredforconsolidationofsynapticplasticityaswellasformationoflong-termmemory.RegulatesendocytosisofAMPAreceptorsinresponsetosynapticactivity.RequiredforhomeostaticsynapticscalingofAMPAreceptors(Bysimilarity). SIZE:396aminoacids;45316Da SUBUNIT:InteractswithSH3GL1/endophilin-2,SH3GL3/endophilin-3andDNM2/DYN2(Bysimilarity). SUBCELLULARLOCATION:Cytoplasm,cytoskeleton(Bysimilarity).Endosome(Bysimilarity).Acrosome(Bysimilarity).Celljunction,synapse,postsynapticcellmembrane,postsynapticdensity(Bysimilarity).Cellprojection,dendrite(Bysimilarity).Cellprojection,dendriticspine(Bysimilarity).Celljunction,synapse(Bysimilarity).Note=Associatedwiththecellcortexofneuronalsomaanddendrites.Enrichedinpostsynapticdensityofdendriticspines.Associatedwiththespermtail(Bysimilarity). SIMILARITY:SwissProt:Q7LC44##BelongstotheARC/ARG3.1family. |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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vectorlabs/Biotinylated Aleuria Aurantia Lectin (AAL)/B-1395/1 mg
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Mouse IgG)/PK-6102/1 kit
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Universal)/PK-6200/1 kit
vectorlabs/Unconjugated Musa Paradisiaca (Banana) Lectin (BanLec)/L-1410/5 mg
GiottoBiotech/Calmodulin N60D/5 mg/G02CLM60cn