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Millipore/AB5802 | Anti-Dopamine Transporter Antibody, extracellular Loop 2/AB5802/100 µL188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Millipore/AB5802 | Anti-Dopamine Transporter Antibody, extracellular Loop 2/AB5802/100 µL

Description
CatalogueNumberAB5802
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-DopamineTransporterAntibody,extracellularLoop2
ProductInformation
FormatAffinityPurified
PresentationAffinitypurifiedimmunoglobulin.Eachvialcontains~33μgofaffinity-purifiedantibodyin100μLof10mMHEPES(pH7.5),150mMNaClwith100μg/mLBSAand50%glycerol.
StorageandShippingInformation
StorageConditionsMaintainat-20to-80°Cinundilutedaliquotsforuptosixmonths.StoreinaNON-self-defrostingfreezer.Avoidrepeatedfreeze-thawcycles.
Applications
ApplicationAnti-DopamineTransporterAntibody,extracellularLoop2isanantibodyagainstDopamineTransporterforuseinIH&WB.
KeyApplications
  • Immunohistochemistry
  • WesternBlotting
ApplicationNotesImmunoblotting:1:500-1:1,000

Immunohistochemistryusingformaldehyde-fixedbrainsections:1:500-1:1,000

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenSyntheticpeptidefromtheEL2regionofhumandopaminetransporter.
EpitopeextracellularLoop2
HostRabbit
SpecificityDopamineTransporter,Extracellularloop2(EL2).
SpeciesReactivity
  • Human
  • Monkey
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryThedopaminetransporter(DAT1)mediatestheactivereuptakeofdopaminefromthesynapseandisaprincipalregulatorofdopaminergicneurotransmission.TheDAT1genehasbeenimplicatedinhumandisorderssuchasparkinsonism,Tourettesyndrome,andsubstanceabuse(Vandenberghetal.,1992[PubMed1359373]).[suppliedbyOMIM]
GeneSymbol
  • SLC6A3
  • ADHD
  • DAT
  • DAT1
  • ADD
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:Q01959#Aminetransporter.Terminatestheactionofdopaminebyitshighaffinitysodium-dependentreuptakeintopresynapticterminals.
SIZE:620aminoacids;68495Da
SUBUNIT:Homooligomer;disulfide-linked.InteractswithPRKCABPandTGFB1I1.
SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
SIMILARITY:SwissProt:Q01959##Belongstothesodium:neurotransmittersymporter(SNF)family.
MISCELLANEOUS:Thisproteinisthetargetofpsychomotorstimulantssuchasamphetaminesorcocaine.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
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