企业QQ
官方微信
Interleukin-35 is a glycosylated, disulfide-linked, heterodimeric protein consisting of the p35 subunit from IL-12 (IL-12α) and the β subunit from IL-27 (EBI3). IL-35 can be expressed by regulatory T-cells (Tregs), macrophages, and certain trophoblast and dendritic cells. It is induced in response to inflammation, and generally acts as an inflammation suppressor. IL-35 suppresses inflammation by exerting multiple activities, including the induction of regulatory T-cells and the suppression of Th17 cells. Recombinant Human IL-35 produced from HEK293 cells is a glycosylated, heterodimeric protein that migrates as a diffuse band centered at an apparent molecular weight of about 60 kDa by SDS-PAGE analysis under non-reducing conditions.
This was determined by SDS-PAGE gel and HPLC analysis.
Measured by its ability to inhibit proliferative activity of PBMCs.
Alpha Subunit:
| RNLPVATPDP | GMFPCLHHSQ | NLLRAVSNML |
| QKARQTLEFY | PCTSEEIDHE | DITKDKTSTV |
| EACLPLELTK | NESCLNSRET | SFITNGSCLA |
| SRKTSFMMAL | CLSSIYEDLK | MYQVEFKTMN |
| AKLLMDPKRQ | IFLDQNMLAV | IDELMQALNF |
| NSETVPQKSS | LEEPDFYKTK | IKLCILLHAF |
| RIRAVTIDRV | MSYLNAS |
Beta Subunit:
| RKGPPAALTL | PRVQCRASRY | PIAVDCSWTL |
| PPAPNSTSPV | SFIATYRLGM | AARGHSWPCL |
| QQTPTSTSCT | ITDVQLFSMA | PYVLNVTAVH |
| PWGSSSSFVP | FITEHIIKPD | PPEGVRLSPL |
| AERQLQVQWE | PPGSWPFPEI | FSLKYWIRYK |
| RQGAARFHRV | GPIEATSFIL | RAVRPRARYY |
| VQVAAQDLTD | YGELSDWSLP | ATATMSLGK |
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.
For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
matriks/Shikari® (S-ATP) Anti-Pembrolizumab ELISA w/confirmation/PEM-QNS-KEY
intactgenomics/Methionine Auxotrophic LBA4404 | ig® | Intact Genomics/15x50μl/1076-15
goprolytix/Proteolytic Activation of Prothrombin/1 mg, 200 µg/BCT-DFP
novateinbio/Dynorphin A ( 13-17 ) Porcine Peptide/5mg/PE-54024_5mg
matriks/Shikari® (Q-ETA) Etanercept ELISA/ETA-FD-ENB
intactgenomics/Agrobacterium ElectroComponent Combo Pack | Intact Genomics/12x50µl/1290-24
Jackson/Peroxidase AffiniPure Goat Anti-Mouse IgG (H+L)/2.0 ml/115-035-003
Jackson/Peroxidase AffiniPure Goat Anti-Rabbit IgG (H+L)/2.0 ml/111-035-003
Qubit™ dsDNA BR Assay Kit Q32853现货
Invitrogen Q32855 Qubit™ RNA HS Assay Kit现货促销
LUCK-1G,D-Luciferin, Potassium Salt 钾盐现货
GoldBio/D-Luciferin, Sodium Salt (Proven and Published™)/LUCNA-1G/1 g