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PhosphoSolutions/Lysosomal Associated Membrane Protein 1 (LAMP1) Antibody/1030-LAMP1/100 µl188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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PhosphoSolutions/Lysosomal Associated Membrane Protein 1 (LAMP1) Antibody/1030-LAMP1/100 µl

Mousemonoclonalantibody

Size:
100µl
Formulation:
ProteinGPurified
Specificity:
Rat,Mouse,Human,Bovine
Applications:
WB1:5,000IF1:1,000
Species:
Mouse
MolecularReference:
~100kDa
CiteThisAntibody:
PhosphoSolutionsCat#1030-LAMP1,RRID:AB_2492140
Antigen/Purification:ExpandCollapse

TheantigenisarecombinantfulllengthhumanLAMP1expressedinandpurifiedfromE.Coli.

TheantibodyisProteinGpurifiedfromtissueculturesupernatant.

 

BIOLOGicalSignificance:ExpandCollapse

LysosomalAssociatedMembraneProtein1(LAMP1)isaproteinthatislocalizedprimarilyinlysosomesbutmayalsobepresentonlateendosomesandtheplasmamembrane.LAMP1antibodiesarethereforewidelyusedaslysosomeMarkers.Ithasrecentlybeensuggestedthatlysosomesareactivatedinmicrogliaintheprogressionofmultiplesystematrophy(MSA)andthusplayakeyroleinitspathology(Makiokaetal.,2012).

Storage

100µlinPBS+10mMsodiumazide.

Forlongtermstorage–20°Cisrecommended.Stableat–20°Cforatleast1year.

GeneralReferences

MakiokaK,YamazakiT,TakatamaM,NakazatoY,OkamotoK.(2012)Activationandalterationoflysosomesinmultiplesystematrophy.Neuroreport.Mar28;23(5):270-6.

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